Recurrent Pregnancy Loss: Causes and Treatment Options

The loss of two or more pregnancies before the 24th week of gestation is defined as recurrent pregnancy loss. Pregnancy loss, a sad reality, occurs in about 15% of all pregnancies. However, fortunately, only 1–2% of couples experience recurrent pregnancy loss.
This means that couples go through a difficult process both physically and mentally. Additionally, as the number of losses increases, the anxiety levels of the couples also rise.
Treatment Options: Antiphospholipid Antibody and Thyroid Function Tests
In cases with a history of recurrent pregnancy loss, low-dose aspirin and low molecular weight heparin are recommended for those who test positive for antiphospholipid antibodies. At the same time, L-thyroxine treatment is recommended for patients with abnormal thyroid function tests and a diagnosis of clinical hypothyroidism.
These treatment options may help increase the chances of couples achieving a healthy pregnancy.
Investigation of Anatomical Abnormalities and Surgical Treatment
In cases of recurrent pregnancy loss, it is important to determine whether there is an anatomical abnormality of the uterus. For this purpose, imaging methods such as three-dimensional ultrasound and hysterosalpingography can be used. If an abnormality is detected, surgical treatment may be recommended. In this way, anatomical problems in the uterus can be corrected, increasing the chance of a healthy pregnancy.
Additional Investigations: Genetic and Immunological Tests
Considering the medical and family history of the couples, additional investigations such as genetic tests, immunological tests, and hereditary thrombophilia tests may also be considered. These tests can help identify possible genetic or immune system problems. In this way, the treatment plan can be shaped more effectively and the chance of achieving a healthy pregnancy can be increased.
Lifestyle Changes and Support
In 60% of cases with recurrent pregnancy loss, the causes leading to miscarriage cannot be determined. In such cases, couples are advised to maintain a balanced and regular diet, keep a normal weight, quit smoking, avoid excessive alcohol, and adopt a healthy lifestyle.
In this way, overall health can be improved and a foundation can be prepared for a healthy pregnancy. Additionally, it is important for couples to receive psychological support during this difficult process. Experts and support groups can help by providing encouragement, answering questions, and offering emotional support.
Recurrent pregnancy loss can be a difficult experience for couples. However, with the right diagnosis and treatment approach, the chances of achieving a healthy pregnancy can be increased.
It is important to use low-dose aspirin and low molecular weight heparin in cases positive for antiphospholipid antibodies, regulate thyroid function tests, surgically correct anatomical abnormalities, and perform additional investigations. Additionally, lifestyle changes and psychological support are among the supportive measures.
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Op. Dr. Soner DÜZGÜNER
Obstetrics and Gynaecology Specialist
Op. Dr. Soner Düzgüner: Provides diagnosis and treatment in areas such as in vitro fertilization, women's health, infertility, gynecological surgery and pregnancy follow-up.