Chromosomal Translocation and In Vitro Fertilization (IVF) Treatment

Chromosomal translocation is the incorrect attachment of a piece of one chromosome to another chromosome. It often goes unnoticed, as the carrier usually does not show any apparent disease.

However, it may appear in cases of recurrent IVF failures, pregnancy losses, or infertility. In these individuals, the possibility of achieving a healthy pregnancy is reduced due to unbalanced gene transfer.

At this point, the recommended step is to perform karyotype analysis, a genetic screening test used to determine whether the person is a carrier of a translocation.

If diagnosed, the most effective method is Preimplantation Genetic Testing (PGT). With this approach, only genetically healthy embryos are selected and transferred during the IVF process.

In conclusion: recurrent failures or pregnancy losses may not simply be coincidences. When underlying genetic causes are identified through proper testing, effective treatment is possible.

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    Op. Dr. Soner DÜZGÜNER

    Obstetrics and Gynaecology Specialist

    Op. Dr. Soner Düzgüner: Provides diagnosis and treatment in areas such as in vitro fertilization, women's health, infertility, gynecological surgery and pregnancy follow-up.